Mega-autophagosome Induction by Human COX-3 and Human Nucleobindin

Authors

Gideon N. Logan, Brigham Young University
Daniel Simmons, Brigham Young University

Keywords

mega-autophagosome induction, human COX-3, human nucleobindin

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Cyclooxygenase (COX) isoenzymes catalyze the first step of prostanoid synthesis, which plays a role in various conditions including pain, inflammation, arthritis, and cancer. Recently our laboratory has shown that mammalian cell lines transfected with the COX-1 splice variant, COX-3, express translationally recoded proteins, including four unglycosylated lower molecular weight forms, 57kDa (57 rcCOX-3), 50kDa (50 rcCOX-3), 47kDa (47 rcCOX-3) and 44kDa (44 rcCOX-3.)

Recommended Citation

Logan, Gideon N. and Simmons, Daniel (2015) "Mega-autophagosome Induction by Human COX-3 and Human Nucleobindin," Journal of Undergraduate Research: Vol. 2015: Iss. 1, Article 190.
Available at: https://scholarsarchive.byu.edu/jur/vol2015/iss1/190