Extent and Mechanism of Translational Readthrough in Humans

Authors

Michael Porter, Brigham Young University
Dr. John Prince, Brigham Young University

Keywords

translational readthrough, codon readthrough, metabolism

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Introduction Proteins are an integral part of the cell. They are responsible for metabolism, DNA replication, transportation, and responding to changes in environment. Because of their importance to the cell, proteins are often drug targets due to the important roles they play in carrying out cellular function. Proteins are made by ribosomes which are responsible for translating proteins from mRNA. The end of translation is signaled by a stop codon in the RNA. However, in some organisms such as viruses and yeast, the stop codon may be bypassed in an event known as translational readthrough.

Recommended Citation

Porter, Michael and Prince, Dr. John (2015) "Extent and Mechanism of Translational Readthrough in Humans," Journal of Undergraduate Research: Vol. 2015: Iss. 1, Article 187.
Available at: https://scholarsarchive.byu.edu/jur/vol2015/iss1/187