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Journal of Undergraduate Research

Keywords

anti-dengue antibodies, dengue virus, Epitope Spreading, EBI2

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Dengue virus is a mosquitoes-borne virus that causes dengue fever. It is found primarily in tropical areas with over a third of the world’s population living in at-risk areas (WHO). The number of infections has grown rapidly in recent years with as many as 50 to 100 million infections occur each year (WHO). Though not widely present in the United States (small outbreaks occur with some regularity in Texas from the Mexican border; Hawaii and Florida relatively recently had cases), many travelers endemic areas contract the virus. Though several are being studied, as yet, there are no vaccines available for dengue. Treatment is for symptoms and for maintenance of vascular volume if dengue hemorrhagic fever occurs. This semester, I have worked primarily on harvesting anti-dengue antibodies produced by memory B cells.

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Microbiology Commons

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