Journal of Undergraduate Research
Keywords
chondrocyte, enhancer elements, intronic region, Col11a2
College
Life Sciences
Department
Physiology and Developmental Biology
Abstract
Osteoarthritis is one of most prominent illnesses that plague our world today. It involves the degeneration of cartilage between joints due to a reduction of collagen fibrils. The type XI collagen gene (Col11a2) is one of a few genes responsible for the production of the collagen fibrils. It is expressed wherever cartilage is present. It is expressed in these areas because of specific expression factors (proteins) that enhance the production of collagen. Once these expression factors are known, a possible genetic remedy can be manufactured to aide in curing osteoarthritis or other skeletal abnormalities.
Recommended Citation
Smith, Steven Alan and Bridgewater, Dr. Laura
(2014)
"Locating Chondrocyte-specific Enhancer Elements in the First Intronic Region of the Col11a2 Gene,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 904.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/904