The Nectin-Zyxin Interaction’s Role in EMT

Authors

Bradley Scott Colton, Brigham Young University
Dr. Marc Hansen, Brigham Young University

Keywords

nectin-zyxin, EMT, VASP, epithelialmesenchymal

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The purpose of our experiment was to prove the interactions between three different proteins named nectin, zyxin, and VASP. It is thought that these proteins are involved in forming interactions with the actin cytoskeleton between neighboring cells and add to the cell adhesion between cells in an epithelial layer of cells. Normally cells need to stick together to function together as a layer of cells. One of the characteristics of cancer is when cells break these cell-to-cell adhesions in order to migrate to different areas of the body and set up new tumor sites. This process is known as epithelialmesenchymal transition.

Recommended Citation

Colton, Bradley Scott and Hansen, Dr. Marc (2014) "The Nectin-Zyxin Interaction’s Role in EMT," Journal of Undergraduate Research: Vol. 2014: Iss. 1, Article 883.
Available at: https://scholarsarchive.byu.edu/jur/vol2014/iss1/883