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Journal of Undergraduate Research

Keywords

rat gene, dietary selenium, glutathione peroxidase, GP, enzyme

College

Life Sciences

Department

Nutrition, Dietetics, and Food Science

Abstract

Various genes have been discovered which are regulated by the dietary Intake of the trace element Selenium (Se).Some of these genes code for such enzymes as glutathione peroxidase (GP J Type I iodothyronine 5′ delodinase (IDI), and selenoproteln P (Se-P). GP, is an enzyme (a selenoenzyme) which Incorporates Se in place of sulfur within residues of the amino acid cysteine. GP, Is active In the assistance of free radical elimination throughout the body by converting hydrogen peroxide (H,02 ) to oxygen (02) and water (H20). IDI is a selenoenzyme which catalyzes the conversion of the thyroid hormone thyroxine (T 4) to its more active form triiodothyronine (TJ. Se-P Is a plasma selenoenzyme whose function has not yet been elucidated.

Included in

Nutrition Commons

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