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Journal of Undergraduate Research

Keywords

HIV, quasi-species, vivo, AIDS, HAART, FDC, genetic sequence

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Human Immunodeficiency Virus (HIV) is the causative agent of Acquired Immunodeficiency Syndrome (AIDS). There is currently no cure for HIV infection, and AIDS has been reported as the fourth highest killer in the world [1]. The initial success of the drug cocktail used in Highly Active Anti-Retroviral Therapy (HAART) has made the possibility of a cure for AIDS seem attainable, however the persistence of virus reservoirs makes this extremely difficult and leads to a rebound of viral load [2]. The known reservoirs of HIV include latently infected T cells, macrophages and follicular dendritic cells.

Included in

Microbiology Commons

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