Journal of Undergraduate Research
Keywords
FDC, HIV POV, HAART, anti-retroviral therapy, immune system
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
Human Immunodeficiency Virus (HIV), the causative agent of AIDS, has eluded successful treatment since its discovery in the early 1980s. The prospect of successful treatment came with the advent of Highly Active Anti-Retroviral Therapy (HAART) which has reduced plasma virus replication to undetectable levels in many patients. Although virus may be maintained below detectable levels for years by treatment, complete viral clearance has not been achieved. “Hidden” reservoirs of non-replicating or slowly replicating virus escape rigorous drug treatment. When the patient is taken off of anti-retroviral therapy, plasma virus levels will return to pre-therapy levels and HIV will continue the course of infection.
Recommended Citation
Rowley, Jesse and Burton, Dr. Gregory
(2014)
"FDCs in HIV Infected Patients Retain Archival HIV Sequences,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 833.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/833