Identification of a Novel Positive Cis-acting Element in the First Intron of the Mouse Col11a2 Gene

Authors

Steven Alan Smith, Brigham Young University
Dr. Laura Bridgewater, Brigham Young University

Keywords

cis-acting element, first intron, Col11a2 gene, F/G, mouse

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Three chondrocyte-specific enhancer elements were previously identified in the mouse type XI collagen gene, Col11a2 (1-3). Enhancer elements are base pair sequences of DNA to which proteins bind enhancing expression of a particular gene. One of these enhancers, called F/G, is located in the first intron of that gene (3). This work has revealed the likely presence of additional positive cis-acting (enhancer) elements in the first intron, and one of those elements has been identified.

Recommended Citation

Smith, Steven Alan and Bridgewater, Dr. Laura (2014) "Identification of a Novel Positive Cis-acting Element in the First Intron of the Mouse Col11a2 Gene," Journal of Undergraduate Research: Vol. 2014: Iss. 1, Article 832.
Available at: https://scholarsarchive.byu.edu/jur/vol2014/iss1/832