Journal of Undergraduate Research
Keywords
Fc receptors, HIV, follicular dendritic cells, FDC, HAART
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
The development of HighlyActive Antiretroviral Therapy (HAART) against the HIV virus created a temporary excitement regarding a possible cure for HIV. This optimism resulted due to the fact that HAART blocked active HIV replication and reduced the level of HIV in the bloodstream to below standard limits of detection. However, it was soon discovered that HIV blood levels were restored shortly after cessation of HAART. This led to the discovery of HIV reservoirs, or sites where latent virus is harbored. It is this harbored virus that actively replicates and replenishes HIV viral loads when HAART is discontinued.
Recommended Citation
Willis, Daniel and Burton, Dr. Gregory
(2014)
"Fc Receptors in HIV Trapping and Retention on Follicular Dendritic Cells,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 830.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/830