Journal of Undergraduate Research
Keywords
vitro effects, follicular dendritic cells, proliferation, HIV, T cells
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
Human Immunodeficiency Virus (HIV), the cause of AIDS, has eluded successful treatment since its discovery in the early 1980s. HIV is a retrovirus that infects and eventually destroys CD4+ T cells. In HIV infected individuals it is believed that during the longest phase of infection (latency) most viral production takes place in and around the germinal centers of secondary lymphoid tissues. Follicular dendritic cells (FDCs) are a unique component of the germinal center, and previous studies done in our laboratory have suggested that FDCs may augment viral replication and/or infection within the germinal center.
Recommended Citation
Rowley, Jesse and Burton, Dr. Gregory
(2014)
"In Vitro Effects of Follicular Dendritic Cells on Proliferation of HIV infected T cells,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 821.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/821