Journal of Undergraduate Research
Keywords
Che, chemotaxis, Pho, phosphate, Escherichia coli, bacteria
College
Life Sciences
Department
Microbiology and Molecular Biology
Abstract
Bacteria live in a continuously changing environment. In order to survive, bacteria must monitor nutrients, acidity, temperature, osmolarity, etc. The use of two-component systems to sense and respond to these environmental changes is a common motif observed in a wide variety of organisms. A two-component system consists of two main proteins, a sensor and a response regulator(2). The sensor protein is a trans-membrane protein which monitors environmental fluctuations and activates the response regulator through phosphorylation. The response regulator contains two domains, the receiver module and the output domain. The receiver module is phosphorylated and dephosphorylated by the sensor protein. Communication between the phosphorylated receiver domain and the output domain subsequently mediates changes in gene expression or locomotion(2).
Recommended Citation
Zumbrennen, Kimberly B. and McCleary, Dr. William R.
(2014)
"Conservation Of The Che And Pho Systems In Escherichia Coli,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 799.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/799