Osteoarthritis and Cartilage

Authors

David Holt, Brigham Young University
Dr. L. C. Bridgewater, Brigham Young University
Dr. R. E. Seegmiller, Brigham Young University

Keywords

osteoarthritis, OA, cartilage, spondyloepiphesial dysplasia congenita, SEDC

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Objective: To test the hypothesis that the spondyloepiphesial dysplasia congenita (sedc) heterozygous (sedc/þ) mouse, a COL2A1 mutant, is a model for the study of osteoarthritis (OA) in the absence of dwarfism and to investigate the presence of HtrA1, Ddr2, and Mmp-13 and their possible involvement in a universal mechanism leading to OA.

Recommended Citation

Holt, David; Bridgewater, Dr. L. C.; and Seegmiller, Dr. R. E. (2014) "Osteoarthritis and Cartilage," Journal of Undergraduate Research: Vol. 2014: Iss. 1, Article 793.
Available at: https://scholarsarchive.byu.edu/jur/vol2014/iss1/793