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Journal of Undergraduate Research

Keywords

endogenous CCL28, chemokines, immune system, bacteria

College

Life Sciences

Department

Microbiology and Molecular Biology

Abstract

Chemokines play a well-characterized and significant role in the immune system as chemoattractants for white blood cells. Some chemokines have also been shown to have antimicrobial properties in addition to their chemoattractant functions. CCL28 is a chemokine that aids in the recruitment of antibody secreting cells to mucosal surfaces of the body, especially in the large intestine and lactating mammary glands.1 Recent research has shown that, in addition to recruiting lymphocytes, CCL28 also exhibits antimicrobial activity against gram positive and gram negative bacteria, and antifungal activity.2

Included in

Microbiology Commons

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