Cytotoxicity of Caffeine, Ephedrine, and Metabolites

Authors

Jennetta Watson, Brigham Young University
Dr. Gary Booth, Brigham Young University

Keywords

cytotoxicity of caffeine, ephedrine, metabolites, energy levels

College

Life Sciences

Department

Biology

Abstract

Caffeine and ephedrine are found together as constituents in a variety of dietary supplements promising to increase metabolism, raise energy levels, and promote weight loss. Much research has been done in this area; however, there is little to no information in the literature about studies focused on the toxicity and anti-proliferative properties of this same caffeine/ephedrine combination occurring at the cellular level. Caffeine’s toxicity against many cell types has been well documented for years.¹ In addition, a number of studies have shown that using caffeine or its metabolites in combination with other chemical or physical reagents increases the overall toxic effect, specifically in regards to cancerous or highly proliferating cells.² Ephedrine and ephedrine type alkaloids have also been shown to have toxic properties.³

Recommended Citation

Watson, Jennetta and Booth, Dr. Gary (2014) "Cytotoxicity of Caffeine, Ephedrine, and Metabolites," Journal of Undergraduate Research: Vol. 2014: Iss. 1, Article 742.
Available at: https://scholarsarchive.byu.edu/jur/vol2014/iss1/742