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Journal of Undergraduate Research

Keywords

material choice, thromboembolism, platelet aggregates, thrombi

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

Abstract

Stroke, heart attack, or other severe medical problems may arise when platelet aggregates block a patient’s blood vessels. These aggregates form when blood is exposed to foreign surfaces in biomedical equipment. When blood is first exposed to a foreign surface, platelets adhere to the surface. A cluster of platelets on the surface is called a thrombus. Thrombi grow as more platelets adhere, and the momentum of passing fluid or other causes may dislodge them. Dislodged thrombi are called emboli, and the entire process is called thromboembolism. Thromboembolism cannot be entirely avoided in blood-contacting devices, such as artificial organs.

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