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Journal of Undergraduate Research

Keywords

encapsulating liposomes, drug delivery, tumors

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

Abstract

Liposomes are tiny vesicles composed of materials similar to a cell membrane’s bilayer and “are useful for delivering anticancer agents to tumors and reducing the severe side effects of the agents.”1 Following synthesis, liposomes containing drug are administered intravenously. Fortunately, tumors have hyperpermeable vasculature which facilitates liposomal accumulation by their leaking out of the capillaries surrounding the tumor.2 Once near the tumor, individual cells will endocytose or engulf the vesicles as long as they are between 10 nm and 1000 nm.3

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