Improved Synthesis of 2-amino-6-alkoxypurineribosides, Potential Co-agents for Combination Therapy with Alkylating Anticancer Drugs

Authors

Dr. Morris J. Robins, Brigham Young University
Dr. Theodore C. Jessop, Brigham Young University

Keywords

2-amino-6-alkoxypurineribosides, therapy, alkylating anticancer drugs

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

2-amino-6-alkoxypurineribosides are involved in clinical testing as anticancer co-drugs (1); however, current methods for the large scale synthesis of these compounds have proven extremely difficult. The improved synthesis of 2-amino-6-alkoxypurineribosides reported herein allows easy access to these medicinally important compounds.

Recommended Citation

Robins, Dr. Morris J. and Jessop, Dr. Theodore C. (2014) "Improved Synthesis of 2-amino-6-alkoxypurineribosides, Potential Co-agents for Combination Therapy with Alkylating Anticancer Drugs," Journal of Undergraduate Research: Vol. 2014: Iss. 1, Article 1153.
Available at: https://scholarsarchive.byu.edu/jur/vol2014/iss1/1153