Journal of Undergraduate Research
Keywords
excision, chicken cyclooxygenase-2. COX, intron 1, prostaglandins
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Cyclooxygenases (COXs) are enzymes that are responsible for the production of a potent class of biological signaling molecules called prostaglandins. Prostaglandins are involved in responses such as inflammation, contraction of smooth muscle, and regulation of water balance in the kidney. They are also found in greatly elevated amounts in some types of cancer. This elevation in prostaglandins is the result of increased production of the form of COX known as COX-2. Because COX-2 may play a role in the development of cancer, an understanding of how COX-2 is regulated is important in the understanding of cancer and may give insights that could lead to a cure.
Recommended Citation
Evanson, Nathan and Simmons, Dr. Daniel L.
(2014)
"Elements Regulating Excision of Chicken Cyclooxygenase-2 Intron 1,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 1146.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/1146