Journal of Undergraduate Research
Keywords
cholic acid-derived antibiotics, electron microscopic analysis, steroid antibiotics
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Pathogenic bacterial resistance to antibiotics has risen sharply over the past two decades.1 This problem is compounded with Gram-negative bacteria, which, in addition to developing specific resistant mechanisms, also display membrane structures that are impermeable to many hydrophobic antibiotics. Thus, new antibiotics are needed that do not elicit the emergence of resistant organisms, especially against Gram-negative bacteria.
Recommended Citation
Jensen, Katie L. and Savage, Dr. Paul B.
(2014)
"Mechanistic Study of Cholic Acid-Derived Antibiotics Synthesis and Electron Microscopic Analysis,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 1139.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/1139