Journal of Undergraduate Research
Keywords
thermodynamics, aqueous nucleic acid bases, nucleosides
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Despite the astounding advances in modern genetics research, surprisingly little is known about the thermodynamic behavior and physical properties of DNA’s molecular subunits. Our study investigated several thermodynamic properties of common nucleic acid constituents. Specifically, we calculated the apparent molar volumes (Vφ) and apparent molar heat capacities (Cp,φ) of the nucleosides adenosine, guanosine, cytidine, thymidine, and uridine, and of their corresponding bases adenine, cytosine, thymine, and uracil, in dilute aqueous solutions.
Recommended Citation
McRae, Bryan R. and Woolley, Dr. Earl M.
(2014)
"Thermodynamics of Aqueous Nucleic Acid Bases and Nucleosides,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 1137.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/1137