Journal of Undergraduate Research
Keywords
gold nanoparticles, membrane-active steroid antibiotics, CSA, cationic steroid-derived antibiotics
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Pathogenic bacterial resistance to antibiotics has risen sharply over the past two decades.1 This problem is compounded with Gram-negative bacteria, which, in addition to developing specific resistant mechanisms, also display membrane structures that are impermeable to many hydrophobic antibiotics. Thus, new antibiotics are needed that do not elicit the emergence of resistant organisms, especially against Gram-negative bacteria.
Recommended Citation
Jensen, Katie L. and Savage, Dr. Paul B.
(2014)
"Use of Gold Nanoparticles to Identify Targets of Membrane-Active Steroid Antibiotics,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 1131.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/1131