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Journal of Undergraduate Research

Keywords

intermolecular tether, photochemical cycloadditions, oxetanocin, Bacillus megaterium

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Oxetanocin is a nucleoside that occurs naturally in the bacteria Bacillus megaterium (see figure 1a).1 Oxetanocin and its analogues show antiviral activity but have not yet been introduced in any successful drug treatment. Even so, oxetanocin continues to be a model studied to help understand the action of nucleoside drugs. Oxetanocin is a distinct nucleoside because it has a four-membered ring sugar moiety.

Included in

Chemistry Commons

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