Journal of Undergraduate Research
Keywords
reductive animation, benzylamine-borane, air stable complex
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Reductive amination is an important method used to generate amines from aldehydes or ketones. This process occurs in a two-step in situ reaction. First, an iminium intermediate is formed when the carbonyl compound condenses with ammonia or a primary or secondary amine. This intermediate is then reduced by a reducing agent already present in the reaction mixture (Scheme 1).
Recommended Citation
Bowman, Adam M. and Peterson, Dr. Matt A.
(2014)
"An Efficient Reductive Amination Protocol Using Benzylamine-Borane As Reducing Agent,"
Journal of Undergraduate Research: Vol. 2014:
Iss.
1, Article 1101.
Available at:
https://scholarsarchive.byu.edu/jur/vol2014/iss1/1101