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Journal of Undergraduate Research

Keywords

chronic alcohol intoxication, dopaminergic reward pathway, isoflourane

College

Family, Home, and Social Sciences

Department

Psychology

Abstract

My research project studied the effects of chronic alcohol intoxication on the brain’s pleasure center (the mesocorticolimbic system). I worked with JungJae Park (M.S. in neuroscience) and three other undergraduate students. Because rats dislike the taste of alcohol, we injected the alcohol directly into their abdominal cavity. This was done under isoflourane anesthesia to avoid any discomfort for the animals. We injected three experimental rats an intoxicating dose of alcohol twice daily for three weeks. Three other rats were used as control subjects (received saline injections twice daily).

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