DEVELOPMENT OF NEW LIPID A-BINDING AGENTS

Authors

Mark Benson, Brigham Young University
Dr. Paul B. Savage, Brigham Young University

Keywords

lipid A-binding. polymyxin B, bacterial endotoxin

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

The aim of this project is to synthesize a non-peptide lipid A-binding agent which is less toxic and simpler than polymyxin B. Such a binding agent could be used to fight sepsis, a toxic condition where the body overreacts to the lipid A portion of bacterial endotoxin released by Gram-negative bacteria.

Recommended Citation

Benson, Mark and Savage, Dr. Paul B. (2013) "DEVELOPMENT OF NEW LIPID A-BINDING AGENTS," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2604.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2604