Effects of Metabolic Rate on Muscle Cell Phospholipid Profile

Authors

Aaron Miller, Brigham Young University
Danny Sims, Brigham Young University
Dr. Steven Wood, Brigham Young University

Keywords

metabolic rate, muscle cell phospholipid profile, ESI-MS, PCA

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Animal and human cell membranes are composed primarily of phospholipids that form a bi-layer around the cell. Phospholipids play a crucial role in cell membrane function by regulating fluidity and structure. Alterations in the cell membrane composition can drastically affect cell function and metabolism. The purpose of our research study was to identify muscle cell membrane compositional changes due to exercise and muscular dystrophy. Also, we sought to identify the specific chemical changes occurring in the cell membrane by characterizing the structures of the cell membrane phospholipids using mass spectrometry.

Recommended Citation

Miller, Aaron; Sims, Danny; and Wood, Dr. Steven (2013) "Effects of Metabolic Rate on Muscle Cell Phospholipid Profile," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2588.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2588