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Journal of Undergraduate Research

Keywords

translational control, Poly(A)-binding protein, hGH, PABP

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Poly(A)-binding protein or PABP is found in high concentrations in all eukaryotic cells. Cell biologists have speculated for a long time that PABP plays an important role in stabilizing the fragile MRNA molecule so that it can be more effectively translated into its final gene product. PABP does this by binding to the Poly(A) tail at the 3′ end of the MRNA. 1,2

Included in

Chemistry Commons

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