Removal of Abundant Non-Informative Proteins from Blood Serum for Biomarker Discovery

Authors

Nathan Lewis, Brigham Young University
Dr. Craig D. Thulin, Brigham Young University

Keywords

non-informative proteins, blood serum, biomarker discovery

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Biomarkers play a key role in disease diagnosis and in guiding physicians in treatment selection. Blood serum is potentially the best tissue for biomarker discovery and detection for several reasons. First, blood is already routinely drawn for tests. Second, serum preparation is highly reproducible between differing labs because the serum preparation method is standardized. Third, the blood is in intimate contact with most other tissues and is often the route by which the body discards of cellular waste or by which endocrine signals are sent.

Recommended Citation

Lewis, Nathan and Thulin, Dr. Craig D. (2013) "Removal of Abundant Non-Informative Proteins from Blood Serum for Biomarker Discovery," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2557.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2557