SOLID PHASE SYNTHESIS OF THE PEPTIDE HULHV AND CHARACTERIZATION USING NUCLEAR MAGNETIC RESONANCE

Authors

Matthew J. Hinton, Brigham Young University
Dr. Roger G. Harrison, Brigham Young University

Keywords

solid phase synthesis, peptide hulhv, nuclear magnetic resonance

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

An exciting area of research is based on the idea that small molecules can be used to perform the same chemical reactions as enzymes. In living organisms, enzymes play important roles in facilitating the vast majority of biochemical reactions necessary for life. One particular class of these biomolecules, non-heme iron containing enzymes, are of particular interest because they have structural characteristics that may allow their chemistry to be modeled by small molecules. In the active site of these enzymes there is often one or more iron atoms bound by two or three histidine side chains. I was interested in determining whether a small, five amino acid peptide with two histidine residues would be able to act in a similar way to these enzymes.

Recommended Citation

Hinton, Matthew J. and Harrison, Dr. Roger G. (2013) "SOLID PHASE SYNTHESIS OF THE PEPTIDE HULHV AND CHARACTERIZATION USING NUCLEAR MAGNETIC RESONANCE," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2555.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2555