Journal of Undergraduate Research
Keywords
molecule-dependent tools, protein function, vivo, Hedgehog, Hh
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
Analyzing the function of newly discovered genes and the proteins that they encode is crucial to the advancement of genetics, cell and molecular biology, and medicine. Scientists have implemented various methods to study individual proteins within a cell, including genetic and small-molecule dependent approaches. Our goal is to combine the generality of genetic manipulation with the time-sensitivity of small-molecule dependence to create tools to study the function of Hedgehog pathway proteins and validate them as drug targets.
Recommended Citation
Dewey, Jonathan and Buskirk, Dr. Allen R.
(2013)
"Engineering Small Molecule-Dependent Tools for the Study of Protein Function In Vivo,"
Journal of Undergraduate Research: Vol. 2013:
Iss.
1, Article 2542.
Available at:
https://scholarsarchive.byu.edu/jur/vol2013/iss1/2542