Optimization of Kidney Cancer Cell Assay Conditions

Authors

Bryce Harbertson, Brigham Young University
Dr. Heidi Vollmer-Snarr, Brigham Young University

Keywords

kidney cancer cell assay, photodynamic therapy, light-sensitive compounds

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Photodynamic therapy involves the use of light-sensitive compounds that, upon irradiation, become lethal to cells. These light-sensitive compounds are referred to as photosensitizers. A class of compounds known as pyridinium bis-retinoids are being investigated as potential photosensitizers, and therefore, chemotherapeutic drugs (Figure 1). One of the primary concerns in these investigations is determining the optimal conditions under which to evaluate these drugs. The optimization of these parameters will allow us to compare the effectiveness of our drugs with others already in existence, and will also serve as a basis for further investigations in animal trials and later on in clinical trials.

Recommended Citation

Harbertson, Bryce and Vollmer-Snarr, Dr. Heidi (2013) "Optimization of Kidney Cancer Cell Assay Conditions," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2538.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2538