Journal of Undergraduate Research
Keywords
HIV integrase inhibitors, synthesis, HTLV
College
Physical and Mathematical Sciences
Department
Chemistry and Biochemistry
Abstract
We have made significant progress toward the synthesis of one branch of the library of compounds that we plan to synthesize. The scheme we have followed is shown below. Once synthesized, we plan to have the compounds tested by expert collaborators to see how well they bind HTLV integrase. In addition, they will be tested against many viruses and cancers, as well as HIV. Because they are nucleoside based, it is impossible to predict exactly what type of biological activity these compounds will have. They could possibly treat a variety of diseases.
Recommended Citation
Jones, Carl and Peterson, Dr. Matt A.
(2013)
"Synthesis of HIV Integrase Inhibitors,"
Journal of Undergraduate Research: Vol. 2013:
Iss.
1, Article 2517.
Available at:
https://scholarsarchive.byu.edu/jur/vol2013/iss1/2517