Use of Cationic Steroid Antibiotics to Fight Drug Resistance in Gram-Positive and Gram-Negative Bacteria

Authors

Thomas Orsak, Brigham Young University
Dr. Paul Savage, Brigham Young University

Keywords

cationic steroid antibiotics, drug resistance, gram-positive, gram-negative, bacteria

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Drug resistance has become an increasing problem for clinical anti-bacterial needs and a major human health threat. Drug resistance emerges through structural or biochemical pathway changes that antibacterial drugs specifically target. Bacteria have the ability to rapidly mutate and gain resistance to antibacterial drugs because of their ability to reproduce rapidly. However some parts of bacterial cells need to stay consistent. The need for consistency for these parts arises from their complexity and their essential biological activities. One of these parts is the bacterial membrane.

Recommended Citation

Orsak, Thomas and Savage, Dr. Paul (2013) "Use of Cationic Steroid Antibiotics to Fight Drug Resistance in Gram-Positive and Gram-Negative Bacteria," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 2514.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/2514