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Journal of Undergraduate Research

Keywords

binding partners, Phosducin, Pdc, G protien

College

Physical and Mathematical Sciences

Department

Chemistry and Biochemistry

Abstract

Cellular signaling is vital to the proper functioning of a cell. In the visual system, as light activates the transmembrane receptor rhodopsin, a series of signals is initiated throughout the cell. This response begins with the activation of G proteins which couple to the rhodopsin. One important player in G protein signaling is Phosducin (Pdc). The unphosphorylated form of Pdc binds to the βγ subunit of the G protein.1 We used a proteomics approach to investigate the possibility of other binding partners for Pdc.

Included in

Chemistry Commons

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