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Journal of Undergraduate Research

Keywords

hypothermia-induced platelet aggregation, fibrinogen funcationality

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

Abstract

Hypothermia-Induced Platelet Aggregation (HIPA) may pose a significant risk for patients undergoing some surgical procedures. During heart surgery, a patient’s core temperature is typically lowered to reduce tissue damage. Hall et al. (2002) observed that this caused blood platelet aggregation in ~30% of test subjects1 and increases post-operative neurological impairment after hypothermic coronary bypass surgery, possibly through occlusion of small blood vessels by platelet aggregates.2

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