Evaluation of Three Chemical Coatings on Biomaterial Induced Thromboembolism

Authors

Joseph Flinders, Brigham Young University
Dr. Kenneth Solen, Brigham Young University

Keywords

chemical coatings, biomaterial induced thromboembolism

College

Ira A. Fulton College of Engineering and Technology

Department

Chemical Engineering

Abstract

When blood contacts man-made biomaterials such as those used in artificial organs (e.g. hemodialyzers, oxygenators, etc.) a chain of events occurs that can lead to medical complications as serious as a stroke. These events include proteins (particularly fibrinogen) adhering to the biomaterial’s surface, the accumulation of blood platelets on the fibrinogen to form “Thrombi”, and then the dislodging of the thrombi to form particles (microemboli) that can block downstream arteries or capillaries causing a “stroke” or other cardiovascular event.

Recommended Citation

Flinders, Joseph and Solen, Dr. Kenneth (2013) "Evaluation of Three Chemical Coatings on Biomaterial Induced Thromboembolism," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1757.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1757