Cell Transfection of Rat Chondrosarcoma Cells Assaying Col11a2 Gene Enhancer Element Activity Using Luciferase and â-galactosidase

Authors

Ann Hillam, Brigham Young University
Dr. Laura C. Bridgewater, Brigham Young University

Keywords

cell transfection, rat chondrosarcoma cells, Col11a2, luciferase, â-galactosidase

College

Life Sciences

Department

Plant and Wildlife Sciences

Abstract

The Col11a2 gene encodes the production of type XI collagen which is fundamental for normal skeletal development. As with many genes, comparatively little is known of the transcriptional activation and enhancement mechanisms of the Col11a2 gene. Such knowledge will help advance gene therapy techniques to minimize and eventually eradicate the negative physical defects effectuated by a mutated Col11a2 gene.

Recommended Citation

Hillam, Ann and Bridgewater, Dr. Laura C. (2013) "Cell Transfection of Rat Chondrosarcoma Cells Assaying Col11a2 Gene Enhancer Element Activity Using Luciferase and â-galactosidase," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1591.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1591