Premature Osteoarthritis in the Temporomandibular Joint of Heterozygous Disporportionate Micromelia Mice

Authors

Jason Farrell, Brigham Young University
Dr. Robert Seegmiller, Brigham Young University

Keywords

premature osteoarthritis, temporomandibular joint, heterozygous, Dmm, Disporportionate micromelia mice

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The purpose of this study, as also summarized in the proposal for this research grant, was to analyze the temporomandibular joints (TMJs) of mice with a specific collagen defect, Disproportionate Micromelia. Examining these joints was done to provide an animal model to be used in Osteoarthritis research, and to propose a potential mechanism for osteoarthritis in this joint in humans. Better understanding of Osteoarthritis in this joint using an animal model can help lead to potential future treatments for a wide variety of TMJ disorders.

Recommended Citation

Farrell, Jason and Seegmiller, Dr. Robert (2013) "Premature Osteoarthritis in the Temporomandibular Joint of Heterozygous Disporportionate Micromelia Mice," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1522.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1522