Effects of AntiViral Drug Compounds in Blocking Influenza Virus M2 Channels in Xenopus Laevis Ooctyes

Authors

Timothy McClain, Brigham Young University
David Busath, Brigham Young University

Keywords

antiviral drug compounds, Influenza, M2, Xenopus Laevis Ooctyes

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The purpose of this project was to research and test various drug compounds to prevent influenza virus infection. A specific target of my research is M2 protein channels that aid in the uncoating of the viral coat. Recent mutations have rendered formerly effective drugs almost completely useless. With recent outbreaks and mutations of the virus, the demand for antiviral drugs has never been greater. The goal of the project was to test several different compounds that had been selected based on unique characteristics, designed to adjust to the mutation, and prevent further infection.

Recommended Citation

McClain, Timothy and Busath, David (2013) "Effects of AntiViral Drug Compounds in Blocking Influenza Virus M2 Channels in Xenopus Laevis Ooctyes," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1518.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1518