Effects of Acetyl-L-carnitine Supplementation on AMPK-Activity and Mitochondrial Biogenesis in LKB1 Knockout Mice

Authors

Lisa McCoy, Brigham Young University
Dr. David Thomson, Brigham Young University

Keywords

acetyl-L-carnitine, AMPK-activity, mitochondrial biogenesis, LKB1, knockout mice

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

During the medical school interview of the school I will be attending next Fall, my interviewer asked me to speak of a time in which I had failed or suffered an obstacle in my academic career. He laughed and said that I probably hadn’t even had one because of the numbers he had observed in my application. I rebutted and told him I very recently had faced difficulty. I spoke of this experience. Throughout my entire academic career, I have never really had to face failure. I was blessed with motivation and the capacity to excel and my grades consistently showed that. This one mistake was a rude awakening. The soleus and plantaris muscles of all of the mice were left outside of the freezer and thawed. When tissues are harvested from mice, we freeze them immediately to preserve the properties of living tissue. Thawed tissue is useless tissue.

Recommended Citation

McCoy, Lisa and Thomson, Dr. David (2013) "Effects of Acetyl-L-carnitine Supplementation on AMPK-Activity and Mitochondrial Biogenesis in LKB1 Knockout Mice," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1517.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1517