Effect of Muscle Stimulation on Gene Expression for Mitochondrial Proteins

Authors

Darren Goring, Brigham Young University
Dr. David Thomson, Brigham Young University

Keywords

muscle stimulation, gene expression, mitochondrial proteins

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The original purpose of this study was to elucidate the effects of muscle stimulation on gene expression for mitochondrial proteins in mLKB1-KO mice (mice in which the LKB1 gene has been knocked out of the muscles and heart). LKB1 is an important protein involved in the signaling of mitochondrial protein production. The original protocol was to run the mice on a treadmill fast enough and long enough to cause transcription of mitochondrial proteins. I hypothesized that the mLKB1-KO mice would still have some mitochondrial gene expression but to a lesser degree than the conditional mice.

Recommended Citation

Goring, Darren and Thomson, Dr. David (2013) "Effect of Muscle Stimulation on Gene Expression for Mitochondrial Proteins," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1509.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1509