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Journal of Undergraduate Research

Keywords

bilayer membrane fusion rates, cholesterol

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

A bilayer is a two-layered membrane made of lipids that form around cells. These membranes are formed by hydrophobic tails (water fearing) and hydrophilic heads (water loving) that align such that the tails are isolated from water, while the heads are exposed to water to form micelles, liposomes, or sheets (Fig. 1). They are used to regulate what can enter and exit a cell. A fusion event occurs when a liposome fuses with a sheet. In our experiments, we are able to see the effects on fusion rate by altering the cholesterol content of the sheets.

Included in

Physiology Commons

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