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Journal of Undergraduate Research

Keywords

CEF-5, SNK, serum induced kinase, chicken embryo fibroblasts

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The malignant transformation of chicken embryo fibroblasts (CEF) following infection with the Rous sarcoma virus is mediated through the oncogene v-src. One of the first responses of infected cells is the transcriptional activation of a set of immediate-early genes. Among these are CEF-5 (homologue of EGRI, early growth response, in mammals) and serum induced kinase (snk).

Included in

Physiology Commons

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