Assessing Premature Arthritis in SEDC Mutant Mice

Authors

Shaela Avery, Brigham Young University
Dr. Robert Seegmiller, Brigham Young University

Keywords

premature arthritis, SEDC mutation, mice, spondyloepiphiseal dysplasia congenita

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

A recently discovered collagen gene mutation, spondyloepiphiseal dysplasia congenita (sedc), is found on the Col2a1 gene in both mice and humans. The mouse mutation is molecularly similar to the human SEDC mutation, which causes premature osteoarthritis. Studies, such as this one, in mouse models provide a greater understanding of this recently discovered mutation and help in finding ways to prevent osteoarthritis in humans.

Recommended Citation

Avery, Shaela and Seegmiller, Dr. Robert (2013) "Assessing Premature Arthritis in SEDC Mutant Mice," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1474.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1474