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Journal of Undergraduate Research

Keywords

vitro examination, cholesterol, vesicle exocytosis, SNARE

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Neurons communicate to other cells by releasing neurotransmitter through a process called exocytosis. Exocytosis of neurotransmitter containing vesicles to their plasma membranes is via the SNARE protein complex. Studies that have examined the SNARE protein complex, using an in vitro lipid bilayer model, have thus far not examined the effects of cholesterol on the SNARE driven fusion. As a research hypothesis, I expect that cholesterol will have a positive effect on the rate of SNARE driven fusion events.

Included in

Physiology Commons

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