Phospholipase A2 Activity in Cell Signaling Apoptotic Pathway

Authors

Vu Mai Phuong, Brigham Young University
Dr. John Bell, Brigham Young University

Keywords

phospholipase A2, sPLA2, cell signaling, apoptotic

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Secretory phospholipase A2 (sPLA2) is a secretory enzyme thought to mainly function in hydrolyzing membrane phospholipids in certain conditions of signaling induced by the immune system or hormone activity. sPLA2 is known to be implicated in inflammatory diseases, sepsis, adult respiratory distress syndrome, ischemia, cancer, atherosclerosis, pre-eclampsia, and gall stones; therefore, understanding its mechanism of action is an important step in helping other researchers determine therapeutic means for these diseases.

Recommended Citation

Phuong, Vu Mai and Bell, Dr. John (2013) "Phospholipase A2 Activity in Cell Signaling Apoptotic Pathway," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1434.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1434