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Journal of Undergraduate Research

Keywords

merocyanine 540, fluorescence, apoptotic lymphocytes, sPLA2, secretory phospholipase A2

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Our research team in Dr. Bell’s laboratory has focused primarily on studying interactions between cell membranes and the enzyme secretory phospholipase A2 (sPLA2). This enzyme is able to distinguish between healthy cells and foreign or damaged cells, which it hydrolyzes. The purpose of my individual project was to use a specific fluorescent probe to study the mechanism for the selective susceptibility and degradation of cell membranes by sPLA2.

Included in

Physiology Commons

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