THE ADRENAL CORTEX CELL LINE H295R RELEASES INTERLEUKIN-6

Authors

Timothy E. Lindsay, Brigham Young University
Dr. Allan M. Judd, Brigham Young University

Keywords

adrenal cortex, H295R, interleukin-6, bovine models

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

Up to this point, the study of adrenal glands has utilized mostly rat and bovine models. However, in the research of human physiology, human models are preferable to animal models. But human adrenal glands are difficult to obtain, and when they are obtained, experiments often have limited sample sizes. In addition, human adrenal glands available for research are often functionally altered by disease. Also, donors with healthy adrenal glands may be administered multiple pharmacological agents which modify adrenal functions. These obstacles show how a model that provides an unlimited quantity of tissue with consistent secretion patterns would take precedent over donated human adrenal glands.

Recommended Citation

Lindsay, Timothy E. and Judd, Dr. Allan M. (2013) "THE ADRENAL CORTEX CELL LINE H295R RELEASES INTERLEUKIN-6," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1423.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1423