Does Addition of the SNARE protein SNAP-25 to Syntaxin 1A Enhance Fusion Rates of Modified Synaptic Vesicles in a System Containing the Minimum Vesicle Fusion Machinery?

Authors

Jeremy Curtis, Brigham Young University
Dr. Dixon Woodbury, Brigham Young University

Keywords

SNARE, SNAP-25, syntaxin 1A, fusion rates, vesicle fusion

College

Life Sciences

Department

Physiology and Developmental Biology

Abstract

The original intent of my project was to compare the fusion rates of synaptic vesicles to a syntaxin artificial membrane with and without SNAP-25. Recent research has shown that modified synaptic vesicles may fuse to a syntaxin-only bilayer . Prior to this, the major dogma of the SNARE-induced hypothesis of vesicle fusion has included SNAP-25 as a necessary component.

Recommended Citation

Curtis, Jeremy and Woodbury, Dr. Dixon (2013) "Does Addition of the SNARE protein SNAP-25 to Syntaxin 1A Enhance Fusion Rates of Modified Synaptic Vesicles in a System Containing the Minimum Vesicle Fusion Machinery?," Journal of Undergraduate Research: Vol. 2013: Iss. 1, Article 1416.
Available at: https://scholarsarchive.byu.edu/jur/vol2013/iss1/1416